The Pathophysiology and Management of NAFDL in Post-menopausal Women: An Updated Short Review

Abstract

Non Alcoholic Fatty Liver Disease (NAFDL) is a condition in which an individual suffers from an accumulation of fat in the liver. This is a disease condition with a multifactorial etiology. Some potent causes of such conditions are altered thyroid condition, abnormal metabolism in the body due to aging or menopause, or any other hormonal imbalance. Most of these causes are regulated by genetics, lifestyle, and environmental factors. Menopause comes with tremendous hormonal turmoil in the human body and brings various abnormal conditions that significantly divert from physiological conditions. One such condition that comes along with menopause in women is NAFLD. Also, the progression of NAFDL is more in post-menopausal women than in premenopausal women. This review aims to comprehend and understand from the existing literature if the prevailing NAFLD condition worsens and aggravates in women with menopause or remains unaffected. This short review briefly discusses the pathophysiology of the onset and progression of NAFDL in post-menopausal women. Lifestyle restrictions, diet, proper monitoring, and medications and supplementations are the only ways to manage NAFLD in post-menopausal women. A detailed and better understanding of NAFDL, its onset, progression, and association with the physiological condition of post-menopausal women is necessary to better manage and treat the NAFDL condition in post-menopausal women.