Affiliation:
1. Department of Chemistry, Government General Degree College, West Bengal, India
2. Department of Physiology,
Hooghly Mohsin College, Chinsura, Hooghly, 712 101, West Bengal, India
3. Department of Physiology, Government
General Degree College, West Bengal, India
Abstract
Abstract:
Levothyroxine or l-thyroxine is artificially manufactured thyroxine, which is used as a drug
to treat underactive thyroid conditions in humans. The drug, levothyroxine, is consumed daily in a
prescribed dose to replace the missing thyroid hormone thyroxine in an individual with an underactive
thyroid, and it helps to maintain normal physiological conditions. Though it is a life-maintaining drug,
it replaces the missing thyroid hormone and performs the necessary daily metabolic functions in our
body. Like all other allopathic drugs, it comes with certain side effects, which include joint pain,
cramps in muscle, weight gain/loss, hair loss, etc. The thyroid hormone, thyroxine, is known to mobilize
fat in our body, including the ones from the hepatic system. An underactive thyroid may cause an
accumulation of fat in the liver, leading to a fatty liver, which is clinically termed Non-Alcoholic Fatty
Liver Disease (NAFLD). The correlation between hypothyroidism and NAFLD is now well-studied
and recognized. As levothyroxine performs the functions of the missing thyroxine, it is anticipated,
based on certain preliminary studies, that the drug helps to mobilize hepatic fat and thus may have a
crucial role in mitigating the condition of NAFDL.
Publisher
Bentham Science Publishers Ltd.
Subject
Drug Discovery,Pharmacology,General Medicine
Cited by
1 articles.
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