The Effect of Selective Hypothermia of the Cerebral Cortex on Metabolism in Patients with Prolonged Impairment of Consciousness

Author:

Mengistu Elias M.ORCID,Petrova Marina V.ORCID,Shevelev Oleg A.ORCID

Abstract

A pilot study was conducted among patients with chronic impaired consciousness in order to assess the response of energy expenditure at rest (REE) during craniocerebral hypothermia. It was found that REE increased in 70.59% of patients, and decreased in 29.41%. It is assumed that the decrease in REE is associated with preserved metabolic activity in the intact parts of the cerebral cortex and may indicate the presence of rehabilitation potential, and the decrease indicates the presence of gross damage that excluded the selectivity of hypothermic exposure.

Publisher

Federal Research and Clinical Center for Resuscitation and Rehabilitation

Subject

General Medicine

Reference2 articles.

1. Торосян Б.Д., Бутров А.В., Шевелев О.А., и др. Влияние краниоцеребральной гипотермии на метаболизм у пациентов в остром периоде ишемического инсульта // Медицинский алфавит. 2018. Т. 1, № 9. С. 41−44. [Torosyan BD, Burov AV, Shevelev OA, et al. Effect of craniocerebral hypothermia on metabolism in patients with acute ischemic stroke. Medical alphabet. 2018;1(9):41–44. (In Russ).]

2. Craniocerebral hypothermia as a therapeutic treatment option for thermal balance disturbances in post-comatose patients

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