Probing mechanisms of resistance to the tuberculosis drug isoniazid: Conformational changes caused by inhibition of InhA, the enoyl reductase fromMycobacterium tuberculosis-Reference-Cited by-同舟云学术

Probing mechanisms of resistance to the tuberculosis drug isoniazid: Conformational changes caused by inhibition of InhA, the enoyl reductase fromMycobacterium tuberculosis

Published:2007-08 Issue:8 Volume:16 Page:1617-1627
ISSN:0961-8368
Container-title:Protein Science
language:en
Short-container-title:Protein Sci.

Author:

Kruh Nicole A.,Rawat Richa,Ruzsicska Béla P.,Tonge Peter J.

Publisher

Wiley

Subject

Molecular Biology,Biochemistry

Reference29 articles.

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3. Mechanisms of isoniazid resistance in Mycobacterium tuberculosis: Enzymatic characterization of enoyl reductase mutants identified in isoniazid-resistant clinical isolates;Basso;J. Infect. Dis.,1998

4. Calculating sedimentation coefficient distributions by direct modeling of sedimentation velocity concentration profiles;Dam;Methods Enzymol.,2004

5. Crystal structure and function of the isoniazid target of Mycobacterium tuberculosis;Dessen;Science,1995

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4. Disruption of key NADH-binding pocket residues of the Mycobacterium tuberculosis InhA affects DD-CoA binding ability;Scientific Reports;2017-07-05

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