The conserved AAA-ATPase PCH-2TRIP13regulates spindle checkpoint strength-Reference-Cited by-同舟云学术

The conserved AAA-ATPase PCH-2TRIP13regulates spindle checkpoint strength

Published:2020-09-15 Issue:20 Volume:31 Page:2219-2233
ISSN:1059-1524
Container-title:Molecular Biology of the Cell
language:en
Short-container-title:MBoC

Author:

Défachelles Lénaïg¹,Russo Anna E.¹,Nelson Christian R.¹,Bhalla Needhi¹

Affiliation:

1. Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA 95064

Abstract

The length of the cell cycle delay imposed by the spindle checkpoint, also referred to as the spindle checkpoint strength, is controlled by the number of unattached kinetochores, cell volume, and cell fate. We show that PCH-2, a highly conserved AAA-ATPase, controls checkpoint strength during early embryogenesis in C. elegans.

Publisher

American Society for Cell Biology (ASCB)

Subject

Cell Biology,Molecular Biology

Reference74 articles.

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