Affiliation:
1. Broad Institute of Harvard and MIT, Cambridge, MA 02142
Abstract
Clinical sequencing uncovers many variants of unknown significance, especially in cancer, leaving doctors stuck. We show that cell morphology-specifically, images of cells stained for various organelles through the Cell Painting assay-contains sufficient information to determine the impact of many variants on diverse genes and functions.
Publisher
American Society for Cell Biology (ASCB)
Subject
Cell Biology,Molecular Biology
Cited by
35 articles.
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