Cell Painting, a high-content image-based assay for morphological profiling using multiplexed fluorescent dyes-Reference-Cited by-同舟云学术

Cell Painting, a high-content image-based assay for morphological profiling using multiplexed fluorescent dyes

Published:2016-08-25 Issue:9 Volume:11 Page:1757-1774
ISSN:1754-2189
Container-title:Nature Protocols
language:en
Short-container-title:Nat Protoc

Author:

Bray Mark-Anthony^ORCID,Singh Shantanu,Han Han,Davis Chadwick T,Borgeson Blake,Hartland Cathy,Kost-Alimova Maria,Gustafsdottir Sigrun M,Gibson Christopher C,Carpenter Anne E

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology

Link

http://www.nature.com/articles/nprot.2016.105.pdf

Reference49 articles.

1. Swinney, D.C. & Anthony, J. How were new medicines discovered? Nat. Rev. Drug Discov. 10, 507–519 (2011).

2. Swinney, D.C. The contribution of mechanistic understanding to phenotypic screening for first-in-class medicines. J. Biomol. Screen. 18, 1186–1192 (2013).

3. Moffat, J.G., Joachim, R. & David, B. Phenotypic screening in cancer drug discovery — past, present and future. Nat. Rev. Drug Discov. 13, 588–602 (2014).

4. Johannessen, C.M., Clemons, P.A. & Wagner, B.K. Integrating phenotypic small-molecule profiling and human genetics: the next phase in drug discovery. Trends Genet. 31, 16–23 (2015).

5. Bickle, M. The beautiful cell: high-content screening in drug discovery. Anal. Bioanal. Chem. 398, 219–226 (2010).

Cited by 698 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Multicolor imaging based on brightness coded set;Optics and Lasers in Engineering;2025-01

2. Decoding phenotypic screening: A comparative analysis of image representations;Computational and Structural Biotechnology Journal;2024-12

3. Applying cell painting in non-tumorigenic breast cells to understand impacts of common chemical exposures;Toxicology in Vitro;2024-12

4. High-Throughput Transcriptomics Screen of ToxCast Chemicals in U-2 OS Cells;Toxicology and Applied Pharmacology;2024-10

5. Extrapolating Lessons from Targeted Protein Degradation to Other Proximity-Inducing Drugs;ACS Chemical Biology;2024-09-12