Cell Painting, a high-content image-based assay for morphological profiling using multiplexed fluorescent dyes
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Biochemistry, Genetics and Molecular Biology
Link
http://www.nature.com/articles/nprot.2016.105.pdf
Reference49 articles.
1. Swinney, D.C. & Anthony, J. How were new medicines discovered? Nat. Rev. Drug Discov. 10, 507–519 (2011).
2. Swinney, D.C. The contribution of mechanistic understanding to phenotypic screening for first-in-class medicines. J. Biomol. Screen. 18, 1186–1192 (2013).
3. Moffat, J.G., Joachim, R. & David, B. Phenotypic screening in cancer drug discovery — past, present and future. Nat. Rev. Drug Discov. 13, 588–602 (2014).
4. Johannessen, C.M., Clemons, P.A. & Wagner, B.K. Integrating phenotypic small-molecule profiling and human genetics: the next phase in drug discovery. Trends Genet. 31, 16–23 (2015).
5. Bickle, M. The beautiful cell: high-content screening in drug discovery. Anal. Bioanal. Chem. 398, 219–226 (2010).
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