Coordinated changes in cell membrane and cytoplasm during maturation of apoptotic bleb

Author:

Aoki Kana1,Satoi Shinsuke1,Harada Shota2,Uchida Seiichi2,Iwasa Yoh13,Ikenouchi Junichi145

Affiliation:

1. Department of Biology, Faculty of Sciences, Kyushu University, Fukuoka 819-0395, Japan

2. Department of Advanced Information Technology, Kyushu University, Fukuoka 819-0395, Japan

3. Department of Biosciences, School of Science and Technology, Kwansei-Gakuin University, Sanda, Hyogo 669-1337, Japan

4. Japan Science and Technology Agency, Saitama 332-0012, Japan

5. AMED-PRIME, Japan Agency for Medical Research and Development, Tokyo 100-0004, Japan

Abstract

In the course of apoptosis, blebs eventually mature into apoptotic bodies that have immune-modulating activities. We clarified changes that occur in the cell membrane during apoptosis, and that those changes are essential for the formation of apoptotic bodies.

Publisher

American Society for Cell Biology (ASCB)

Subject

Cell Biology,Molecular Biology

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