Genetic interactions between the DBL-1/BMP-like pathway anddpybody size–associated genes inCaenorhabditis elegans-Reference-Cited by-同舟云学术

Genetic interactions between the DBL-1/BMP-like pathway anddpybody size–associated genes inCaenorhabditis elegans

Published:2019-12-15 Issue:26 Volume:30 Page:3151-3160
ISSN:1059-1524
Container-title:Molecular Biology of the Cell
language:en
Short-container-title:MBoC

Author:

Lakdawala Mohammed Farhan¹,Madhu Bhoomi¹,Faure Lionel¹,Vora Mehul²,Padgett Richard W.²³⁴,Gumienny Tina L.¹

Affiliation:

1. Department of Biology, Texas Woman’s University, Denton, TX 76204-5799

2. Waksman Institute of Microbiology, Rutgers University, Piscataway, NJ 08854-8020

3. Waksman Institute of Microbiology Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, NJ 08854-8020

4. Cancer Institute of New Jersey, Rutgers University, Piscataway, NJ 08854-8020

Abstract

How BMP signaling and other body size regulators interact is not clear. We found interactions between Caenorhabditis elegans DBL-1/BMP and ECM, proteins that may modify or secrete DBL-1, and the SET domain protein BLMP-1. DBL-1 signaling may control downstream targets, some through BLMP-1, that affect size either directly or by feeding back on DBL-1 signaling.

Publisher

American Society for Cell Biology (ASCB)

Subject

Cell Biology,Molecular Biology

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