Molecular mechanisms underlying cellular effects of human MEK1 mutations-Reference-Cited by-同舟云学术

Molecular mechanisms underlying cellular effects of human MEK1 mutations

Published:2021-04-19 Issue:9 Volume:32 Page:974-983
ISSN:1059-1524
Container-title:Molecular Biology of the Cell
language:en
Short-container-title:MBoC

Author:

Marmion Robert A.¹,Yang Liu¹,Goyal Yogesh¹²³,Jindal Granton A.¹²⁴,Wetzel Joshua L.¹⁵,Singh Mona¹⁵,Schüpbach Trudi⁶,Shvartsman Stanislav Y.¹²⁶⁷

Affiliation:

1. Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544

2. Department of Chemical and Biological Engineering, Princeton University, Princeton, NJ 08544

3. Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104

4. Department of Medicine, University of California San Diego, La Jolla, CA 92093

5. Department of Computer Science, Princeton University, Princeton, NJ 08540

6. Department of Molecular Biology, Princeton University, Princeton, NJ 08544

7. Flatiron Institute, Simons Foundation, New York, NY 10010

Abstract

Genetics and quantitative imaging studies in Drosophila provide insights into molecular and network-level effects caused by pathogenic mutations affecting a core cell signaling kinase.

Publisher

American Society for Cell Biology (ASCB)

Subject

Cell Biology,Molecular Biology

Reference64 articles.

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5. MEK genomics in development and disease

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