A Raf-induced allosteric transition of KSR stimulates phosphorylation of MEK-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

A Raf-induced allosteric transition of KSR stimulates phosphorylation of MEK

Published:2011-03-27 Issue:7343 Volume:472 Page:366-369
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Brennan Damian F.,Dar Arvin C.,Hertz Nicholas T.,Chao William C. H.,Burlingame Alma L.,Shokat Kevan M.,Barford David

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature09860.pdf

Reference39 articles.

1. Kornfeld, K., Hom, D. B. & Horvitz, H. R. The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans . Cell 83, 903–913 (1995)

2. Sundaram, M. & Han, M. The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Ras-mediated signal transduction. Cell 83, 889–901 (1995)

3. Therrien, M. et al. KSR, a novel protein kinase required for RAS signal transduction. Cell 83, 879–888 (1995)

4. Clapéron, A. & Therrien, M. KSR and CNK: two scaffolds regulating RAS-mediated RAF activation. Oncogene 26, 3143–3158 (2007)

5. Kolch, W. Coordinating ERK/MAPK signalling through scaffolds and inhibitors. Nature Rev. Mol. Cell Biol. 6, 827–837 (2005)

Cited by 215 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Signaling from RAS to RAF: The Molecules and Their Mechanisms;Annual Review of Biochemistry;2024-08-02

2. DCAF7 Acts as A Scaffold to Recruit USP10 for G3BP1 Deubiquitylation and Facilitates Chemoresistance and Metastasis in Nasopharyngeal Carcinoma;Advanced Science;2024-07-08

3. The CNK–HYP scaffolding complex promotes RAF activation by enhancing KSR–MEK interaction;Nature Structural & Molecular Biology;2024-02-22

4. Targeting CRAF kinase in anti-cancer therapy: progress and opportunities;Molecular Cancer;2023-12-18

5. Navigating the ERK1/2 MAPK Cascade;Biomolecules;2023-10-20

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号京ICP备18003416号-3