Affiliation:
1. University of the Philippines Los Banos
Abstract
Objective: Green microalgae are fast growing organisms and are known to have diverse bioactive compounds and biomolecules. The chemical composition and antibacterial activities of a green microalga, A. dimorphus BIOTECH 4039 were studied.
Material and Method: Dried algal biomass of A. dimorphus was subjected to proximate and elemental composition analysis. Methanolic extract of A. dimorphus was used to determine the total phenolic content and antibacterial activity of the microalga. The antibacterial activity against medically important bacterial pathogens was done using modified Kirby-Bauer inhibition assay.
Results and Discussion: Acutodesmus dimorphus contained high amounts of protein, ash, and lipid with percent composition of 43.19 ± 0.13, 26.92 ± 0.01, and 14.17 ± 0.04, respectively. The elemental nutrient composition of the algal biomass was observed to be in a decreasing order of Ca > Mg > K > Mn > Na > Fe > Zn > Pb > Cu > Cd >Cr. In addition, A. dimorphus has a TPC of 5.34 ± 0.09 mg GAE/g. Potent antibacterial activities of A. dimorphus extract were observed against Methicillin-Resistant Staphylococcus aureus, S. epidermidis, penicillin acylase-producing Bacillus cereus with zones of inhibition of 15.1 ± 0.3 mm, 13.5 ± 0.1 mm, and 6.82 ± 0.7 mm, respectively. The study shows the use of A. dimorphus as good alternative source of important compounds and microelements that can be use in industrial and pharmaceutical application.
Publisher
Ankara Universitesi Eczacilik Fakultesi Dergisi
Subject
Pharmaceutical Science,Pharmacology
Reference28 articles.
1. [1] Arguelles, E.D.L.R. (2022). Total phenolic content and In vitro analysis of antioxidant, antibacterial, and alpha-glucosidase inhibition properties of Chroococcus minutus (Kützing) Nägeli (Chroococcales, Cyanobacteria). Ankara Universitesi Eczacilik Fakultesi Dergisi. 46(1), 170-181.
2. [2] Arguelles, E.D.L.R. (2021). Biochemical composition and bioactive properties of Chlorella minutissima (Chm1) as a potential source of chemical compounds for nutritional feed supplement and disease control in aquaculture. Current Applied Science and Technology, 21(1),65-77.
3. [3] Katircioglu, H., Beyalti, Y., Aslim, B., Yusekdag, Z., Atic, T. (2006). Screening for antimicrobial agent production of some microalgae in freshwater. The Internet Journal of Microbiology. 2(2),63-72.
4. [4] Choochote, W., Suklampoo, L., Ochaikul, D. 2014. Evaluation of antioxidant capacities of green microalgae. Journal of Applied Phycology, 26(1), 43-48.
5. [5] Martinez-Goss, M.R., Manlapas, J.E.B., Arguelles, E.D.L.R. (2019). Cyanobacteria and diatoms in the cyanobacterial mats in a natural saltwater hot spring in Coron, Palawan, Philippines. Philippine Science Letters, 12(Supplement), 11–32.
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