A conceptual framework for nomenclatural stability and validity of medically important fungi: a proposed global consensus guideline for fungal name changes supported by ABP, ASM, CLSI, ECMM, ESCMID-EFISG, EUCAST-AFST, FDLC, IDSA, ISHAM, MMSA, and MSGERC

Author:

de Hoog Sybren12345ORCID,Walsh Thomas J.678910ORCID,Ahmed Sarah A.126ORCID,Alastruey-Izquierdo Ana61112ORCID,Alexander Barbara D.1013,Arendrup Maiken Cavling1415ORCID,Babady Esther1016ORCID,Bai Feng-Yan1718192021,Balada-Llasat Joan-Miquel1022,Borman Andrew23ORCID,Chowdhary Anuradha1224,Clark Andrew1025,Colgrove Robert C.2627,Cornely Oliver A.28122930,Dingle Tanis C.103132,Dufresne Philippe J.103133,Fuller Jeff1034,Gangneux Jean-Pierre2835,Gibas Connie36,Glasgow Heather1037,Gräser Yvonne38,Guillot Jacques2139,Groll Andreas H.1240ORCID,Haase Gerhard41,Hanson Kimberly1042ORCID,Harrington Amanda1043,Hawksworth David L.4445464748,Hayden Randall T.103137ORCID,Hoenigl Martin4928505152ORCID,Hubka Vit53,Johnson Kristie1054,Kus Julianne V.105556ORCID,Li Ruoyu35571215,Meis Jacques F.1572930ORCID,Lackner Michaela658,Lanternier Fanny59,Leal Jr. Sixto M.10493160ORCID,Lee Francesca1025,Lockhart Shawn R.1061ORCID,Luethy Paul1054ORCID,Martin Isabella1062,Kwon-Chung Kyung J.63ORCID,Meyer Wieland964,Nguyen M. Hong10496566ORCID,Ostrosky-Zeichner Luis4967,Palavecino Elizabeth1068,Pancholi Preeti1022ORCID,Pappas Peter G.4960,Procop Gary W.10316970ORCID,Redhead Scott A.971,Rhoads Daniel D.727374ORCID,Riedel Stefan1075ORCID,Stevens Bryan1066,Sullivan Kaede Ota1076,Vergidis Paschalis1077ORCID,Roilides Emmanuel6281278,Seyedmousavi Amir10122179,Tao Lili1080,Vicente Vania A.4,Vitale Roxana G.8182ORCID,Wang Qi-Ming83,Wengenack Nancy L.1077ORCID,Westblade Lars1084,Wiederhold Nathan1049316536,White Lewis85ORCID,Wojewoda Christina M.86ORCID,Zhang Sean X.61087ORCID

Affiliation:

1. Radboudumc-CWZ Centre of Expertise for Mycology , Nijmegen, the Netherlands

2. Foundation Atlas of Clinical Fungi , Hilversum, the Netherlands

3. Department of Dermatology and Venereology, Peking University First Hospital , Beijing, China

4. Department of Basic Pathology, Federal University of Paraná , Curitiba, Brazil

5. Research Center for Medical Mycology, Peking University , Beijing, China

6. International Society for Human and Animal Mycology (ISHAM), Working Group Nomenclature

7. Center for Innovative Therapeutics and Diagnostics , Richmond, Virginia, USA

8. University of Maryland School of Medicine , Baltimore, Maryland, USA

9. Nomenclature Committee for Fungi, International Mycological Association (IMA)

10. Fungal Diagnostics Laboratory Consortium (FDLC)

11. Mycology Reference Laboratory, Spanish National Centre for Microbiology , Madrid, Spain

12. Fungal Infection Study Group, European Society of Clinical Microbiology and Infectious Diseases (EFISG/ESCMID) , Basel, Switzerland

13. Departments of Medicine and Pathology, Duke University , Durham, North Carolina, USA

14. Department of Microbiology and Infection Control, Statens Serum Institut, Copenhagen, Denmark; Department of Clinical Microbiology, Copenhagen University Hospital Rigshospitalet , Copenhagen, Denmark

15. Antifungal Susceptibility Testing Subcommittee of European Committee of Antimicrobial Susceptibility Testing (EUCAST-AFST)

16. Clinical Microbiology Service, Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center , New York, USA

17. Mycology Committee of Chinese Society for Microbiology

18. Institute of Microbiology, State Key Laboratory of Mycology, Chinese Academy of Sciences , Beijing, China

19. Medical Mycology Society of Chinese Medicine and Education Association

20. Asia Pacific Society for Medical Mycology

21. ISHAM Working Group Veterinary Mycology and One Health

22. Clinical Microbiology at The Ohio State University Wexner Medical Center , Columbus, Ohio, USA

23. National Mycology Reference Laboratory, Public Health England , Bristol, United Kingdom

24. Department of Microbiology, National Reference Laboratory for Antimicrobial Resistance in Fungal Pathogens, Medical Mycology Unit, Vallabhbhai Patel Chest Institute, University of Delhi , Delhi, India

25. University of Texas Southwestern Medical Center , Dallas, Texas, USA

26. Division of Infectious Diseases, Mount Auburn Hospital , Cambridge, Massachusetts, USA

27. Infectious Diseases Society of America (ISDA)

28. European Confederation of Medical Mycology (ECMM)

29. University of Cologne, Faculty of Medicine, Institute of Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases , Cologne, Germany

30. Department I of Internal Medicine, University of Cologne, Excellence Center for Medical Mycology , Cologne, Germany

31. Clinical and Laboratory Standards Institute (CLSI)

32. Alberta Precision Laboratories, Public Health Laboratory , Calgary, Alberta, Canada

33. Mycology Department, Laboratoire de Santé Publique du Québec, Institut National de Santé Publique du Québec (INSPQ), Sainte-Anne-de-Bellevue , Québec, Canada

34. Department of Pathology and Laboratory Medicine, London Health Sciences Center , London, Ontario, Canada

35. Department of Mycology, Centre Hospitalier Universitaire de Rennes , Rennes, France

36. University of Texas Health Science Center , San Antonio, Texas, USA

37. Clinical and Molecular Microbiology, Department of Pathology, St. Jude Children’s Research Hospital , Memphis, Tennessee, USA

38. Department of Parasitology (Charité), Institute of Microbiology and Hygiene, Humboldt University , Berlin, Germany

39. Onoris, École Nationale Vétérinaire, Agroalimentaire et de l'Alimentation Nantes-Atlantique , Nantes, France

40. Infectious Disease Research Program, Department of Pediatric Hematology and Oncology and Center for Bone Marrow Transplantation, University Children’s Hospital , Münster, Germany

41. Laboratory Diagnostic Center, RWTH Aachen University Hospital , Aachen, Germany

42. University of Utah School of Medicine , Salt Lake City, Utah, USA

43. Loyola University Health System, Loyola University Chicago , Maywood, Illinois, USA

44. Royal Botanic Gardens, Kew , Richmond, Surrey, United Kingdom

45. Natural History Museum , London, United Kingdom

46. University of Southampton , Southampton, United Kingdom

47. Jilin Agricultural University , Chanchung, China

48. General Committee for Nomenclature, International Botanical Congress (IBC)

49. Mycoses Study Group, Education and Research Consortium (MSG-ERC)

50. Division of Infectious Diseases, Medical University of Graz , Graz, Austria

51. Translational Medical Mycology Research Unit, ECMM Excellence Center for Medical Mycology, Medical University of Graz , Graz, Austria

52. European Hematology Association, Specialized Working Group for Infections in Hematology , The Hague, the Netherlands

53. Department of Botany, Charles University , Prague, Czechia

54. Clinical Microbiology Laboratory, UMMC Laboratories of Pathology, University of Maryland School of Medicine , Baltimore, Maryland, USA

55. Public Health Ontario , Toronto, Ontario, Canada

56. Department of Laboratory Medicine and Pathobiology, Canada and University of Toronto , Toronto, Ontario, Canada

57. ISHAM Working Group on Diagnostics

58. Institute of Hygiene and Medical Microbiology, Medical University of Innsbruck , Innsbruck, Austria

59. Institut Pasteur , Paris, France

60. University of Alabama at Birmingham , Birmingham, Alabama, USA

61. Centers for Disease Control and Prevention , Atlanta, Georgia, USA

62. Dartmouth Health , Lebanon, New Hampshire, USA

63. National Institute of Allergy and Infectious Diseases, National Institutes of Health , Bethesda, Maryland, USA

64. Westerdijk Fungal Biodiversity Institute , Utrecht, The Netherlands

65. Medical Mycological Society of the Americas (MMSA)

66. University of Pittsburgh Medical Center , Pittsburgh, Pennsylvania, USA

67. University of Texas Health Science Center at Houston , Houston, Texas, USA

68. Clinical Microbiology Laboratory, Wake Forest Baptist Medical Center , Winston-Salem, North Carolina, USA

69. The American Board of Pathology , Tampa, Florida, USA

70. American Board of Pathology (ABP)

71. National Mycological Herbarium, Ottawa Research and Development Centre, Science and Technology Branch, Agriculture & Agri-Food Canada , Ottawa, Ontario, Canada

72. Cleveland Clinic Lerner College of Medicine, Case Western Reserve University , Cleveland, Ohio, USA

73. Department of Laboratory Medicine, Cleveland Clinic , Cleveland, Ohio, USA

74. Infection Biology Program, Lerner Research Institute, Cleveland Clinic , Cleveland, Ohio, USA

75. Beth Israel Deaconess Medical Center , Boston, Massachusetts, USA

76. Lewis Katz School of Medicine, Temple University , Philadelphia, Pennsylvania, USA

77. Mayo Clinic , Rochester, Minnesota, USA

78. Hippokration Hospital , Thessaloniki, Greece

79. Microbiology Service, Department of Laboratory Medicine, Clinical Center, National Institutes of Health , Bethesda, Maryland, USA

80. Vanderbilt University Medical Center , Nashville, Tennessee, USA

81. Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET) , Buenos Aires, Argentina

82. Unidad de Parasitología, Sector Micología, Hospital J.M. Ramos Mejía , Buenos Aires, Argentina

83. Engineering Laboratory of Microbial Breeding and Preservation of Hebei Province, School of Life Sciences, Institute of Life Sciences and Green Development, Hebei University , Baoding, China

84. Department of Pathology and Laboratory Medicine, Weill Cornell Medical College , New York, USA

85. Public Health Wales Microbiology , Cardiff, United Kingdom

86. Department of Pathology and Laboratory Medicine, University of Vermont Medical Center , Burlington, Vermont, USA

87. Johns Hopkins University School of Medicine , Baltimore, Maryland, USA

Abstract

ABSTRACT The rapid pace of name changes of medically important fungi is creating challenges for clinical laboratories and clinicians involved in patient care. We describe two sources of name change which have different drivers, at the species versus the genus level. Some suggestions are made here to reduce the number of name changes. We urge taxonomists to provide diagnostic markers of taxonomic novelties. Given the instability of phylogenetic trees due to variable taxon sampling, we advocate to maintain genera at the largest possible size. Reporting of identified species in complexes or series should where possible comprise both the name of the overarching species and that of the molecular sibling, often cryptic species. Because the use of different names for the same species will be unavoidable for many years to come, an open access online database of the names of all medically important fungi, with proper nomenclatural designation and synonymy, is essential. We further recommend that while taxonomic discovery continues, the adaptation of new name changes by clinical laboratories and clinicians be reviewed routinely by a standing committee for validation and stability over time, with reference to an open access database, wherein reasons for changes are listed in a transparent way.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference65 articles.

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2. The Amsterdam Declaration on Fungal Nomenclature

3. Report on botanical nomenclature—Melbourne 2011. XVIII International Botanical Congress, Melbourne: Nomenclature Section, 18–22 July 2011

4. McNeill J , Barrie F , Buck W , Demoulin V , We G , Hawksworth D , Herendeen P , Knapp S , Marhold K , Prado J . 2012. International code of nomenclature for algae, fungi and plants (Melbourne code). Vol. 154. Koeltz scientific books, Königstein.

5. Guarro J , Gené J , Ahmed SA , Al-Hatmi AMS , Figueras MJ , Vitale RG . 2020. Atlas of clinical fungi. 4th ed, p 1599. Foundation Atlas of Clinical Fungi, Hilversum.

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