Author:
Johnson M K,Geoffroy C,Alouf J E
Abstract
The binding of cholesterol by pneumolysin, alveolysin, and streptolysin O has been demonstrated. The properties of the cytolysin-cholesterol interaction parallel those of cytolysin-erythrocyte interaction in that the reaction is rapid, temperature independent, decreased at elevated pH, and shows the same specificity with respect to other related sterols. However, oxidized or p-hydroxymercuribenzoate-treated thoxin showed no decrease in cholesterol-binding activity, whereas the ability of cytolysin to bind to erythrocytes was modified by such treatment.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
Reference21 articles.
1. Purification de l'hemolysine thiol-dependante extracellulaire de Bacillus alvei;Alouf J. E.;Biochimie,1977
2. Action de la streptolysine 0 sur les membranes cellulaires. I. Fixation sur la membrane 6rythrocytaire;Alouf J. E.;Ann. Inst. Pasteur,1968
3. Interaction between membranes and cytolytic bacterial toxins;Bernheimer A. W.;Biochim. Biophys. Acta,1974
4. Bernheimer A. W. 1976. Sulfhydryl activated toxins p. 85-97. In A. W. Bernheimer (ed.) Mechanisms of bacterial toxinology. John Wiley & Sons Inc. New York.
5. Inactivation of pneumococcal hemolysin by certain sterols;Cohen B.;Proc. Soc. Exp. Biol. Med.,1937
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