Genetic Environment of Acquired bla ACC-1 β-Lactamase Gene in Enterobacteriaceae Isolates-Reference-Cited by-同舟云学术

Genetic Environment of Acquired bla ACC-1 β-Lactamase Gene in Enterobacteriaceae Isolates

Published:2006-12 Issue:12 Volume:50 Page:4177-4181
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Doloy A.¹,Verdet C.¹²,Gautier V.¹,Decré D.¹,Ronco E.³,Hammami A.⁴,Philippon A.⁵,Arlet G.¹²

Affiliation:

1. Université Paris VI, UPRES EA 2392, UFR de Médecine Pierre et Marie Curie, Paris, France

2. AP-HP, Hôpital Tenon, Service de Bactériologie, Paris, France

3. AP-HP, Hôpital Raymond Poincaré, Laboratoire de Microbiologie, Garches, France

4. Service de Microbiologie, CHU Habib Bourguiba, Sfax, Tunisia

5. AP-HP, Hôpital Cochin, Service de Bactériologie, Paris, France

Abstract

ABSTRACT We studied the genetic organization of bla ACC-1 in 14 isolates of Enterobacteriaceae from France, Tunisia, and Germany. In a common ancestor, IS Ecp1 was likely involved in the mobilization of this gene from the Hafnia alvei chromosome to a plasmid. Other genetic events involving insertion sequences (particularly IS 26 ), transposons (particularly Tn 1696 ), or sulI -type integrons have occurred, leading to complex genetic environments.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00619-06

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