Outbreak of OXY-2-Producing Klebsiella oxytoca in a Renal Transplant Unit-Reference-Cited by-同舟云学术

Outbreak of OXY-2-Producing Klebsiella oxytoca in a Renal Transplant Unit

Published:2008-06 Issue:6 Volume:46 Page:2099-2101
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Zárate Mariela Soledad¹,Gales Ana C.²,Picão Renata C.²,Pujol Gervasio Soler³,Lanza Alejandra¹,Smayevsky Jorgelina¹

Affiliation:

1. Laboratorio de Bacteriología, Micología y Parasitología

2. Laboratorio ALERTA, Disciplina de Infectologia, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brasil

3. Sección de Nefrología, Centro de Educación Médica e Investigaciones Clínicas Norberto Quirno (CEMIC), Ciudad Autónoma de Buenos Aires, Argentina

Abstract

ABSTRACT We describe a Klebsiella oxytoca infection outbreak in a renal transplant unit that involved seven patients. All strains belonged to a single pulsed-field gel electrophoresis pattern and were resistant to amoxicillin-clavulanate, cefuroxime, piperacillin-tazobactam, and aztreonam but susceptible to ceftriaxone, ceftazidime, cefepime, and imipenem. Chromosomal β-lactamase hyperproduction was caused by a point mutation in the bla OXY-2 gene promoter region.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00194-08

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