Efflux Pump Antibiotic Binding Site Mutations Are Associated with Azithromycin Nonsusceptibility in Clinical Neisseria gonorrhoeae Isolates
Author:
Affiliation:
1. Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA
2. Division of Infectious Diseases, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Funder
HHS | NIH | National Institute of Allergy and Infectious Diseases
National Science Foundation
Richard and Susan Smith Family Foundation
Publisher
American Society for Microbiology
Subject
Virology,Microbiology
Link
https://journals.asm.org/doi/pdf/10.1128/mBio.01509-20
Reference13 articles.
1. Cryo-EM Structures of a Gonococcal Multidrug Efflux Pump Illuminate a Mechanism of Drug Recognition and Resistance
2. Ma KC Mortimer TD Hicks AL Wheeler NE Sánchez-Busó L Golparian D Taiaroa G Rubin DH Wang Y Williamson DA Unemo M Harris SR Grad YH. 2020. Increased antibiotic susceptibility in Neisseria gonorrhoeae through adaptation to the cervical environment. bioRxiv doi:10.1101/2020.01.07.896696.
3. Antimicrobial Resistance in Neisseria gonorrhoeae in the 21st Century: Past, Evolution, and Future
4. Azithromycin Resistance through Interspecific Acquisition of an Epistasis-Dependent Efflux Pump Component and Transcriptional Regulator in Neisseria gonorrhoeae
5. Ma KC Mortimer TD Duckett MA Hicks AL Wheeler NE Sánchez-Busó L Grad YH. 2020. Increased power from bacterial genome-wide association conditional on known effects identifies Neisseria gonorrhoeae macrolide resistance mutations in the 50S ribosomal protein L4. bioRxiv doi:10.1101/2020.03.24.006650.
Cited by 15 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Structural and functional diversity of Resistance-Nodulation-Division (RND) efflux pump transporters with implications for antimicrobial resistance;Microbiology and Molecular Biology Reviews;2024-09-05
2. Impact of mutations in the mtrR, rpdlVD and rrl genes on azithromycin resistance in Neisseria gonorrhoeae;PLOS ONE;2024-07-16
3. The novel 2024 WHO Neisseria gonorrhoeae reference strains for global quality assurance of laboratory investigations and superseded WHO N. gonorrhoeae reference strains—phenotypic, genetic and reference genome characterization;Journal of Antimicrobial Chemotherapy;2024-06-21
4. Genomic surveillance and antimicrobial resistance determinants in Neisseria gonorrhoeae isolates from Uganda, Malawi and South Africa, 2015–20;Journal of Antimicrobial Chemotherapy;2023-06-23
5. Functionally distinct mutations within AcrB underpin antibiotic resistance in different lifestyles;npj Antimicrobials and Resistance;2023-05-10
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3