Examination of Genome-Wide Ortholog Variation in Clinical and Environmental Isolates of the Fungal Pathogen Aspergillus fumigatus-Reference-Cited by-同舟云学术

Examination of Genome-Wide Ortholog Variation in Clinical and Environmental Isolates of the Fungal Pathogen Aspergillus fumigatus

Published:2022-08-30 Issue:4 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Horta Maria Augusta C.¹^ORCID,Steenwyk Jacob L.²^ORCID,Mead Matthew E.³²^ORCID,dos Santos Luciano H. Braz⁴^ORCID,Zhao Shu⁵⁶,Gibbons John G.⁵⁶⁷^ORCID,Marcet-Houben Marina⁸⁹,Gabaldón Toni⁸⁹¹⁰¹¹,Rokas Antonis³²^ORCID,Goldman Gustavo H.¹^ORCID

Affiliation:

1. Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, São Paulo, Brazil

2. Vanderbilt Evolutionary Studies Initiative, Vanderbilt University, Nashville, Tennessee, USA

3. Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee, USA

4. Brazilian Agricultural Research Corporation, Embrapa Agroenergy, Brasília, Brazil

5. Molecular and Cellular Biology Graduate Program, University of Massachusetts, Amherst, Massachusetts, USA

6. Department of Food Science, University of Massachusetts, Amherst, Massachusetts, USA

7. Organismic and Evolutionary Biology Graduate Program, University of Massachusetts, Amherst, Massachusetts, USA

8. Barcelona Supercomputing Centre, Barcelona, Spain

9. Institute for Research in Biomedicine, The Barcelona Institute of Science and Technology, Barcelona, Spain

10. Catalan Institution for Research and Advanced Studies, Barcelona, Spain

11. Centro de Investigación Biomédica En Red de Enfermedades Infecciosas, Barcelona, Spain

Abstract

Aspergillus fumigatus is a cosmopolitan species of fungus responsible for thousands of cases of invasive disease annually. Clinical and environmental isolates of A. fumigatus exhibit extensive phenotypic differences, including differences related to virulence and antifungal drug resistance.

Funder

Fundação de Amparo à Pesquisa do Estado de São Paulo

MCTI | Conselho Nacional de Desenvolvimento Científico e Tecnológico

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.01519-22

Reference82 articles.

1. Aspergillus fumigatus and Aspergillosis in 2019