In vitro antifungal activity of pneumocandin L-743,872 against a variety of clinically important molds-Reference-Cited by-同舟云学术

In vitro antifungal activity of pneumocandin L-743,872 against a variety of clinically important molds

Published:1997-08 Issue:8 Volume:41 Page:1835-1836
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Del Poeta M¹,Schell W A¹,Perfect J R¹

Affiliation:

1. Division of Infectious Diseases and International Health, Duke University Medical Center, Durham, North Carolina 27710, USA.

Abstract

The in vitro activity of the new antifungal drug pneumocandin L-743,872 against 55 isolates of clinically important molds was examined by an adapted macrobroth dilution method for yeasts. Pneumocandin L-743,872 exhibited in vitro antifungal activity against Alternaria sp., Aspergillus flavus, Aspergillus fumigatus, Curvularia lunata, Exophiala jeanselmei, Fonsecaea pedrosoi, Paecilomyces variotii, and Scedosporium apiospermum. The drug appeared to lack significant in vitro inhibitory activity against Fusarium oxysporum, Fusarium solani, Rhizopus arrhizus, Paecilomyces lilacinus, and Scedosporium prolificans.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.41.8.1835

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