In vitro evaluation of voriconazole against some clinically important fungi

Author:

McGinnis M R1,Pasarell L1,Sutton D A1,Fothergill A W1,Cooper C R1,Rinaldi M G1

Affiliation:

1. Department of Pathology and WHO Collaborating Center for Tropical Diseases, University of Texas Medical Branch, Galveston 77555-0609, USA.

Abstract

Voriconazole was compared to amphotericin B, fluconazole, and itraconazole by using an in vitro macrobroth dilution test based upon current National Committee for Clinical Laboratory Standards tentative standards against the dimorphic fungi and several opportunistic molds and yeasts. In all instances, the voriconazole MICs were lower than those of fluconazole. In most instances, the MICs were lower than the recorded MICs of amphotericin B and itraconazole.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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