Vancomycin resistance is encoded on a pheromone response plasmid in Enterococcus faecium 228-Reference-Cited by-同舟云学术

Vancomycin resistance is encoded on a pheromone response plasmid in Enterococcus faecium 228

Published:1990-02 Issue:2 Volume:34 Page:358-360
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Handwerger S¹,Pucci M J¹,Kolokathis A¹

Affiliation:

1. Department of Medicine, Beth Israel Medical Center, Mount Sinai School of Medicine, New York, New York 10003.

Abstract

In Enterococcus faecium 228, vancomycin resistance is encoded on a 55-kilobase conjugative plasmid, pHKK100. This plasmid was transferred with high frequency into susceptible strains of Enterococcus faecalis and conferred responses to pheromones produced by E. faecalis and Streptococcus sanguis. pHKK100 is the first plasmid described that mediates both vancomycin resistance and pheromone response.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.34.2.358

Reference22 articles.

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