Helicobacter pylori Initiates the Stringent Response upon Nutrient and pH Downshift-Reference-Cited by-同舟云学术

Helicobacter pylori Initiates the Stringent Response upon Nutrient and pH Downshift

Published:2006-05-15 Issue:10 Volume:188 Page:3726-3729
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Wells Derek H.¹,Gaynor Erin C.²

Affiliation:

1. Department of Biological Sciences, Stanford University, Stanford, California

2. Department of Microbiology and Immunology, Stanford University, Stanford, California

Abstract

ABSTRACT Helicobacter pylori was previously reported to lack a stringent response. In contrast, we show that after nutrient downshift, H. pylori produced abundant ppGpp and less total RNA. pH downshift also caused (p)ppGpp accumulation. Our observations indicate that nutrient deprivation and acid shock activate the stringent response in H. pylori .

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.188.10.3726-3729.2006

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