Complex Association of Virus- and Host-Related Factors with Hepatocellular Carcinoma Rate following Hepatitis C Virus Clearance-Reference-Cited by-同舟云学术

Complex Association of Virus- and Host-Related Factors with Hepatocellular Carcinoma Rate following Hepatitis C Virus Clearance

Published:2019-01 Issue:1 Volume:57 Page:
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Akuta Norio¹²,Suzuki Fumitaka¹²,Sezaki Hitomi¹²,Kobayashi Masahiro¹²,Fujiyama Shunichiro¹²,Kawamura Yusuke¹²,Hosaka Tetsuya¹²,Kobayashi Mariko³,Saitoh Satoshi¹²,Suzuki Yoshiyuki¹²,Arase Yasuji¹²,Ikeda Kenji¹²,Kumada Hiromitsu¹²

Affiliation:

1. Department of Hepatology, Toranomon Hospital, Tokyo, Japan

2. Okinaka Memorial Institute for Medical Research, Tokyo, Japan

3. Liver Research Laboratory, Toranomon Hospital, Tokyo, Japan

Abstract

Little is known about the effects of virus- and host-related factors on hepatocarcinogenesis in patients who show viral clearance after HCV RNA eradication by direct-acting antivirals (DAAs). The subjects of this retrospective study were 1,922 patients with HCV genotype 1 (HCV-1)- or HCV-2-related chronic liver disease who showed a sustained virological response (SVR; defined as negative results for HCV RNA at 12 weeks after the cessation of all-oral DAAs).

Funder

Japan Agency for Medical Research and Development

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.01463-18

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