Studies of Intestinal Microflora VI. Effect of X Irradiation on the Fecal Microflora of the Rat-Reference-Cited by-同舟云学术

Studies of Intestinal Microflora VI. Effect of X Irradiation on the Fecal Microflora of the Rat

Published:1967-08 Issue:2 Volume:94 Page:378-382
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Klainer Albert S.¹²,Gorbach Sherwood¹²,Weinstein Louis¹²

Affiliation:

1. Infectious Disease Service, New England Medical Center Hospitals, Boston, Massachusetts 02111

2. Department of Medicine, Tufts University School of Medicine, Boston, Massachusetts 02111

Abstract

The effect of sublethal, midlethal, and lethal doses of total-body X irradiation on the fecal microbial population of the rat was studied. No changes were observed in animals receiving sublethal doses of X ray. Midlethal and lethal doses produced an increase in the numbers of fecal coliforms, staphylococci, streptococci, and fungi; these changes were transient in rats that survived, but were more marked and persisted during life in those that died. The possible role of these alterations in intestinal microflora in post-irradiation infection and in death is discussed.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jb.94.2.378-382.1967

Reference2 articles.

1. BENNETT L. R. P. E. RETKERS M. KRESGE AND AND J. W. HOWLAND. 1949. The influence of infection on the hematological effects and mortality following midlethal X-irradiation. U.S. Atomic Energy Comm. UR-76.

2. Studies on the effect of roentgen rays upon intestinal epithelium and upon reticuloendothelial cells of liver and spleen;CHROM S. A.;Acta Radiol.,1935

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