High-Fiber, Whole-Food Dietary Intervention Alters the Human Gut Microbiome but Not Fecal Short-Chain Fatty Acids

Author:

Oliver Andrew1ORCID,Chase Alexander B.2,Weihe Claudia3,Orchanian Stephanie B.1ORCID,Riedel Stefan F.1,Hendrickson Clark L.1,Lay Mi1,Sewall Julia Massimelli14,Martiny Jennifer B. H.3ORCID,Whiteson Katrine1ORCID

Affiliation:

1. Department of Molecular Biology and Biochemistry, University of California, Irvine, California, USA

2. Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, La Jolla, California, USA

3. Department of Ecology and Evolutionary Biology, University of California, Irvine, California, USA

4. Faculty of Science and Engineering, Maastricht University, Maastricht, Netherlands

Abstract

A profound decrease in the consumption of dietary fiber in many parts of the world in the last century may be associated with the increasing prevalence of type II diabetes, colon cancer, and other health problems. A typical U.S. diet includes about ∼15 g of fiber per day, far less fiber than the daily recommended allowance.

Funder

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modeling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

Reference89 articles.

1. CODEX-aligned dietary fiber definitions help to bridge the ‘fiber gap’

2. US Department of Agriculture, Agricultural Research Service. 2012. Nutrient intakes from food: mean amounts consumed per individual, by gender and age, what we eat in America, NHANES 2009–2010. US Department of Agriculture, Washington, DC.

3. Gut bacteria selectively promoted by dietary fibers alleviate type 2 diabetes

4. Carbohydrate quality and human health: a series of systematic reviews and meta-analyses

5. Diet, microorganisms and their metabolites, and colon cancer

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