Early-Life Immune System Maturation in Chickens Using a Synthetic Community of Cultured Gut Bacteria

Author:

Zenner Christian12ORCID,Hitch Thomas C. A.2,Riedel Thomas34,Wortmann Esther2,Tiede Stefan34,Buhl Eva M.5,Abt Birte34,Neuhaus Klaus6ORCID,Velge Philippe7ORCID,Overmann Jörg348,Kaspers Bernd1,Clavel Thomas2ORCID

Affiliation:

1. Department for Veterinary Sciences, Veterinary Immunology Study Group, Ludwig-Maximilians-University Munich, Munich, Germany

2. Functional Microbiome Research Group, RWTH University Hospital, Aachen, Germany

3. Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany

4. German Center for Infection Research (DZIF), Partner site Hannover-Braunschweig, Braunschweig, Germany

5. Electron Microscopy Facility, Institute of Pathology, RWTH University Hospital Aachen, Aachen, Germany

6. Core Facility Microbiome, ZIEL Institute for Food & Health, Technical University of Munich, Freising, Germany

7. ISP, INRAE, Université François Rabelais de Tours, UMR 1282, Nouzilly, France

8. Faculty of Life Sciences, Braunschweig University of Technology, Braunschweig, Germany

Abstract

The immune system plays a crucial role in sustaining animal health. Its development is markedly influenced by early microbial colonization of the gastrointestinal tract.

Funder

Deutsche Forschungsgemeinschaft

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modelling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

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