Affiliation:
1. Dipartimento di Biotecnologie Cellulari ed Ematologia, University “La Sapienza,” Rome, Italy
Abstract
ABSTRACT
We report a case of disseminated
Scedosporium apiospermum
infection in a neutropenic patient with acute myeloid leukemia. Due to progression of the mycosis after 7 days of amphotericin B lipid complex therapy and to high susceptibility of the mold to voriconazole in vitro, the patient was treated with intravenous voriconazole. After a few days of therapy, fever disappeared and skin lesions improved. However, the patient died after 1 month due to intestinal bleeding. Despite a negative outcome, this case seems to indicate a promising role for voriconazole in the treatment of
S. apiospermum
infections.
Publisher
American Society for Microbiology
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