“ Mycobacterium tilburgii ,” a Newly Described, Uncultivated Opportunistic Pathogen

Author:

Palmore Tara N.1,Shea Yvonne R.2,Conville Patricia S.2,Witebsky Frank G.2,Anderson Victoria L.1,Rupp Hodge Irene P.3,Holland Steven M.1

Affiliation:

1. Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland

2. Microbiology Service, Department of Laboratory Medicine, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland

3. Rochester Infectious Disease, Frisbie Memorial Hospital, Rochester, New Hampshire

Abstract

ABSTRACT Molecular methods are increasingly used to identify pathogens that are difficult to cultivate. We report a case of disseminated infection with “ Mycobacterium tilburgii ,” a proposed species that has never been cultivated. The case illustrates the diagnostic utility of sequence analysis of the 16S rRNA gene directly from clinical specimens.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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5. Kiratisin, P., L. Li, P. R. Murray, and S. H. Fischer. 2003. Identification of bacteria recovered from clinical specimens by 16S rRNA gene sequencing. Eur. J. Clin. Microbiol. Infect. Dis.22:628-631.

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