Detection of HIV-1 at between 20 and 49 Copies per Milliliter by the Cobas TaqMan HIV-1 v2.0 Assay Is Associated with Higher Pretherapy Viral Load and Less Time on Antiretroviral Therapy-Reference-Cited by-同舟云学术

Detection of HIV-1 at between 20 and 49 Copies per Milliliter by the Cobas TaqMan HIV-1 v2.0 Assay Is Associated with Higher Pretherapy Viral Load and Less Time on Antiretroviral Therapy

Published:2010-05 Issue:5 Volume:48 Page:1911-1912
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Pascual-Pareja José F.¹,Martínez-Prats Lorena¹,Luczkowiak Joanna¹,Fiorante Silvana²,Rubio Rafael²,Pulido Federico²,Otero Joaquín R.¹,Delgado Rafael¹

Affiliation:

1. Microbiology Department, Hospital Universitario 12 de Octubre, Madrid, Spain

2. HIV Unit, Department of Internal Medicine, Hospital Universitario 12 de Octubre, Madrid, Spain

Abstract

ABSTRACT New commercial techniques for determination of the viral load (VL) in plasma are able to detect as few as 20 copies of HIV-1 RNA/ml. The relevance of this new technical threshold is uncertain. Upon multivariate analysis, factors associated with detection of VLs between 20 and 49 copies/ml by the Cobas TaqMan HIV-1 v2.0 assay in an HIV clinic were the basal VL and time on antiretroviral therapy.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.02388-09

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