Evaluation of Archival HIV DNA in Brain and Lymphoid Tissues-Reference-Cited by-同舟云学术

Evaluation of Archival HIV DNA in Brain and Lymphoid Tissues

Published:2023-06-29 Issue:6 Volume:97 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Oliveira Michelli F.¹^ORCID,Pankow Alec²,Vollbrecht Thomas¹³,Kumar Nikesh M.¹,Cabalero Gemma¹,Ignacio Caroline¹,Zhao Mitchell¹,Vitomirov Andrej¹,Gouaux Ben¹,Nakawawa Masato¹,Murrell Ben¹,Ellis Ronald J.⁴,Gianella Sara¹^ORCID

Affiliation:

1. Department of Medicine, University of California San Diego, La Jolla, California, USA

2. Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden

3. Veterans Affairs San Diego Healthcare System, San Diego, California, USA

4. Department of Neurosciences and Psychiatry, University of California San Diego, La Jolla, California, USA

Abstract

HIV infection of the brain is associated with adverse neuropsychiatric outcomes, despite efficient antiretroviral treatment. HIV may persist in reservoirs in the brain and other tissues, which can seed virus replication if treatment is interrupted, representing a major challenge to cure HIV.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.00543-23

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