Required Gene Set for Autotrophic Growth of Clostridium autoethanogenum

Author:

Woods Craig1,Humphreys Christopher M.1,Tomi-Andrino Claudio123,Henstra Anne M.1,Köpke Michael4,Simpson Sean D.4,Winzer Klaus1ORCID,Minton Nigel P.15ORCID

Affiliation:

1. Clostridia Research Group, BBSRC/EPSRC Synthetic Biology Research Centre (SBRC), Biodiscovery Institute, School of Life Sciences, The University of Nottingham, Nottingham, United Kingdom

2. Centre for Analytical Bioscience, Advanced Materials and Healthcare Technologies Division, School of Pharmacy, The University of Nottingham, Nottingham, United Kingdom

3. BBSRC/EPSRC Synthetic Biology Research Centre (SBRC), School of Mathematical Sciences, The University of Nottingham, Nottingham, United Kingdom

4. LanzaTech, Inc., Skokie, Illinois, USA

5. NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, United Kingdom

Abstract

Although microbial genome sequences are relatively easily determined, assigning gene function remains a bottleneck. Consequently, relatively few genes are well characterized, leaving the function of many as either hypothetical or entirely unknown.

Funder

UKRI | Biotechnology and Biological Sciences Research Council

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

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