In VitroCombination of Anidulafungin and Voriconazole against Intrinsically Azole-Susceptible and -Resistant Aspergillus spp.-Reference-Cited by-同舟云学术

In VitroCombination of Anidulafungin and Voriconazole against Intrinsically Azole-Susceptible and -Resistant Aspergillus spp.

Published:2012-05-21 Issue:8 Volume:56 Page:4500-4503
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob. Agents Chemother.

Author:

Planche Virginie,Ducroz Sebastien,Alanio Alexandre,Bougnoux Marie-Elisabeth,Lortholary Olivier,Dannaoui Eric

Abstract

ABSTRACTIn vitrointeraction of anidulafungin with voriconazole was tested by a microdilution broth checkerboard technique and an agar diffusion method against 30Aspergillusclinical isolates belonging to five different species. By using a complete inhibition endpoint, indifferent interactions were observed for 97% of the isolates by the checkerboard technique (FIC index from 0.5 to 2) and for 100% of the isolates by the agar diffusion method (variation of −2 to +1 log2dilutions).

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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