International Multicenter Study To Assess a Panel of Reference Materials for Quantification of Simian Immunodeficiency Virus RNA in Plasma-Reference-Cited by-同舟云学术

International Multicenter Study To Assess a Panel of Reference Materials for Quantification of Simian Immunodeficiency Virus RNA in Plasma

Published:2010-07 Issue:7 Volume:48 Page:2582-2585
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Ham Claire¹,Srinivasan Priya²,Thorstensson Rigmor³,Verschoor Ernst⁴,Fagrouche Zahra⁴,Sernicola Leonardo⁵,Ramos Artur²,Titti Fausto⁵,Almond Neil¹,Berry Neil¹

Affiliation:

1. Division of Retrovirology, NIBSC/HPA, Blanche Lane, South Mimms, Potters Bar, Hertfordshire EN6 3QJ, United Kingdom

2. Laboratory Branch, Division of HIV/AIDS Prevention, National Center for HIV, STD, TB Prevention, CCID, Centers for Disease Control and Prevention, Atlanta, Georgia

3. SIIDC, Solna, Stockholm, Sweden

4. BPRC, Rijswijk, Holland

5. Division of Experimental Retrovirology and Non-Human Primate Models, AIDS National Centre, Instituto Superiore Sanità, Rome, Italy

Abstract

ABSTRACT An international multicenter study was conducted to assess the performance of a panel of simian immunodeficiency virus (SIV) RNA reference materials for plasma viral load determinations. Reliable quantification was demonstrated across an ∼6 log 10 dynamic range. Availability of external reference materials will enable independent calibration of SIV plasma viral load assays.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00082-10

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