Prostaglandin E <sub>2</sub> -Induced Immune Suppression via Cytotoxic T-Lymphocyte Antigen 4 in Paratuberculosis-Reference-Cited by-同舟云学术

Prostaglandin E ₂ -Induced Immune Suppression via Cytotoxic T-Lymphocyte Antigen 4 in Paratuberculosis

Published:2022-10-20 Issue:10 Volume:90 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Sajiki Yamato¹,Konnai Satoru¹²^ORCID,Watari Kei¹,Okagawa Tomohiro²,Tanaka Akina¹,Kawaji Satoko³^ORCID,Nagata Reiko³,Maekawa Naoya²,Suzuki Yasuhiko²⁴,Kato Yukinari⁵⁶,Murata Shiro¹²,Mori Yasuyuki³,Ohashi Kazuhiko¹²

Affiliation:

1. Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan

2. Department of Advanced Pharmaceutics, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan

3. Bacterial and Parasitic Disease Research Division, National Institute of Animal Health, Tsukuba, Japan

4. Division of Bioresources, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Japan

5. Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan

6. Department of Molecular Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan

Abstract

Paratuberculosis is a chronic enteritis of ruminants caused by the facultative intracellular pathogen Mycobacterium avium subsp. paratuberculosis . The Th1 response inhibits the proliferation of M. avium subsp. paratuberculosis during the early subclinical stage.

Funder

MEXT | Japan Society for the Promotion of Science

National Agriculture and Food Research Organization

Ministry of Agriculture, Forestry and Fisheries

Japan Agency for Medical Research and Development

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.00210-22

Reference39 articles.