Streptococcus pneumoniae Isolates with Reduced Susceptibility to Ciprofloxacin in Spain: Clonal Diversity and Appearance of Ciprofloxacin-Resistant Epidemic Clones-Reference-Cited by-同舟云学术

Streptococcus pneumoniae Isolates with Reduced Susceptibility to Ciprofloxacin in Spain: Clonal Diversity and Appearance of Ciprofloxacin-Resistant Epidemic Clones

Published:2001-10 Issue:10 Volume:45 Page:2955-2957
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Alou Luis¹²,Ramirez Mario¹,Garcı́a-Rey César³,Prieto José²,de Lencastre Hermı́nia¹⁴

Affiliation:

1. Molecular Genetics Laboratory, Instituto de Tecnologia Quı́mica e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal1;

2. Microbiology Department, School of Medicine, Universidad Complutense,2 and

3. Medical Department, GlaxoSmithKline Pharmaceuticals,3 Madrid, Spain; and

4. Laboratory of Microbiology, The Rockefeller University, New York, New York4

Abstract

ABSTRACT Analysis of the pulsed-field gel electrophoretic profiles of 82 pneumococcal isolates with reduced susceptibility to ciprofloxacin (RSC) and of 90 co-occurring susceptible isolates indicates a considerable genetic diversity among isolates with RCS and points to a close relation between the two groups. This finding suggests that pneumococci with RCS emerge through independent mutational events.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.45.10.2955-2957.2001

Reference20 articles.

1. Antimicrobial Resistance of 1,113 Streptococcus pneumoniae Isolates from Patients with Respiratory Tract Infections in Spain: Results of a 1-Year (1996–1997) Multicenter Surveillance Study

2. Decreased susceptibility of Streptococcus pneumoniae to fluoroquinolones in Canada.;Chen D. K.;N. Engl. J. Med.,1999

3. Recombinational exchanges at the capsular polysaccharide biosynthetic locus lead to frequent serotype changes among natural isolates of Streptococcus pneumoniae.;Coffey T. J.;Mol. Microbiol.,1998

4. The Three Major Spanish Clones of Penicillin-Resistant Streptococcus pneumoniae Are the Most Common Clones Recovered in Recent Cases of Meningitis in Spain

5. Horizontal Transfer of parC and gyrA in Fluoroquinolone-Resistant Clinical Isolates of Streptococcus pneumoniae

Cited by 39 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Streptococcus pneumoniae;Molecular Medical Microbiology;2015

2. Quinolone Resistance and Its Clinical Relevance;Quinolone Antimicrobial Agents;2014-04-08

3. Nosocomial outbreak of Streptococcus pneumoniae Spain9V‑ST156‑14 clone in a pulmonary diseases ward;Polish Archives of Internal Medicine;2012-07-03

4. Prevalence of Serotype and Multidrug-Resistance of Streptococcus pneumoniae Respiratory Tract Isolates in 265 Adults and 36 Children in Korea, 2002–2005;Microbial Drug Resistance;2010-06

5. Fluoroquinolone Resistance in Streptococcus dysgalactiae subsp. equisimilis and Evidence for a Shared Global Gene Pool with Streptococcus pyogenes;Antimicrobial Agents and Chemotherapy;2010-05