The Fall in Antibody Response to SARS-CoV-2: a Longitudinal Study of Asymptomatic to Critically Ill Patients Up to 10 Months after Recovery-Reference-Cited by-同舟云学术

The Fall in Antibody Response to SARS-CoV-2: a Longitudinal Study of Asymptomatic to Critically Ill Patients Up to 10 Months after Recovery

Published:2021-10-19 Issue:11 Volume:59 Page:
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Peghin Maddalena¹^ORCID,De Martino Maria²,Fabris Martina³,Palese Alvisa⁴,Visintini Erica⁴,Graziano Elena¹⁵,Gerussi Valentina¹⁵,Bontempo Giulia¹⁵,D’Aurizio Federica³,Biasotto Alessia³,Sartor Assunta³,Pipan Corrado³⁵,Marzinotto Stefania³,Curcio Francesco³⁵,Bouza Emilio⁶⁷⁸⁹,Isola Miriam²⁵,Tascini Carlo¹⁵

Affiliation:

1. Infectious Diseases Division, Department of Medicine, University of Udine and Azienda Sanitaria Universitaria Friuli Centrale (ASUFC), Udine, Italy

2. Division of Medical Statistics, Department of Medicine (DAME), University of Udine, Udine, Italy

3. Department of Laboratory Medicine, University of Udine, ASUFC, Udine, Italy

4. Department of Medical Sciences, School of Nursing, University of Udine, Udine, Italy

5. University of Udine, Udine, Italy

6. Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Madrid, Spain

7. Medicine Department, School of Medicine, Universidad Complutense de Madrid, Madrid, Spain

8. Gregorio Marañón Health Research Institute, Madrid, Spain

9. CIBER of Respiratory Diseases (CIBERES CB06/06/0058), Madrid, Spain

Abstract

The aim of this study was to assess the long-term dynamics and factors associated with the serological response against the severe acute respiratory syndrome coronavirus 2 after primary infection. A prospective longitudinal study was conducted with monthly serological follow-up during the first 4 months, and then at 6, 8, and 10 months after the disease onset of all recovered adult in- and outpatients with coronavirus disease 2019 (COVID-19) attending Udine Hospital (Italy) during the first wave (from March to May 2020).

Funder

PRIN

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.01138-21

Reference30 articles.

1. Immune response following infection with SARS‐CoV ‐2 and other coronaviruses: A rapid review

2. Antibody Status and Incidence of SARS-CoV-2 Infection in Health Care Workers

3. Clinical and immunological assessment of asymptomatic SARS-CoV-2 infections