Characterization of Distinct Biofilm Cell Subpopulations and Implications in Quorum Sensing and Antibiotic Resistance-Reference-Cited by-同舟云学术

Characterization of Distinct Biofilm Cell Subpopulations and Implications in Quorum Sensing and Antibiotic Resistance

Published:2022-06-28 Issue:3 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Dodson Taylor A.¹,Carlson Eric A.¹,Wamer Nathan C.¹,Morse Chase N.¹,Gadient Jennifer N.²,Prestwich Erin G.¹^ORCID

Affiliation:

1. Department of Medicinal and Biological Chemistry, University of Toledo, Toledo, Ohio, USA

2. The College of Natural Sciences and Mathematics, NSM Instrumentation Center, University of Toledo, Toledo, Ohio, USA

Abstract

Pseudomonas aeruginosa biofilms can cause chronic infections in burn wounds, grow on medical equipment, and proliferate in the lungs of people with cystic fibrosis. These inherently antibiotic tolerant biofilms are difficult to eradicate largely due to the complexity of the biofilm environment.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

deArce-Koch Memorial Endowment Fund in Support of Medical Research and Development at the University of Toledo

University of Toledo College of Pharmacy and Pharmaceutical Sciences

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.00191-22

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1. Bacterial Differentiation