The Timing and Magnitude of the Type I Interferon Response Are Correlated with Disease Tolerance in Arbovirus Infection-Reference-Cited by-同舟云学术

The Timing and Magnitude of the Type I Interferon Response Are Correlated with Disease Tolerance in Arbovirus Infection

Published:2023-06-27 Issue:3 Volume:14 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Hardy Alexandra¹,Bakshi Siddharth¹,Furnon Wilhelm¹,MacLean Oscar¹,Gu Quan¹,Varjak Margus¹,Varela Mariana¹,Aziz Muhamad Afiq¹,Shaw Andrew E.¹,Pinto Rute Maria¹,Cameron Ruiz Natalia¹,Mullan Catrina¹,Taggart Aislynn E.¹,Da Silva Filipe Ana¹,Randall Richard E.²^ORCID,Wilson Sam J.¹^ORCID,Stewart Meredith E.¹,Palmarini Massimo¹^ORCID

Affiliation:

1. MRC-University of Glasgow Centre for Virus Research, Glasgow, Scotland, United Kingdom

2. School of Biology, Centre for Biomolecular Sciences, University of St. Andrews, St. Andrews, Fife, United Kingdom

Abstract

The host immune response usually aims to inhibit virus replication in order to avoid cell damage and disease. In some cases, however, the infected host avoids the deleterious effects of infection despite high levels of viral replication.

Funder

UKRI | Medical Research Council

Wellcome Trust

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.00101-23

Reference101 articles.

1. Identifying Reservoirs of Infection: A Conceptual and Practical Challenge

2. Host-Pathogen Interactions: Basic Concepts of Microbial Commensalism, Colonization, Infection, and Disease