Murine Toxicity of Cochliobolus carbonum-Reference-Cited by-同舟云学术

Murine Toxicity of Cochliobolus carbonum

Published:1968-11 Issue:11 Volume:16 Page:1719-1722
ISSN:0003-6919
Container-title:Applied Microbiology
language:en
Short-container-title:Appl Microbiol

Author:

Hamilton Pat B.¹²,Nelson R. R.¹²,Harris B. S. H.¹²

Affiliation:

1. Research Triangle Institute, Research Triangle Park, North Carolina 27709

2. Department of Plant Pathology, North Carolina State University, Raleigh, North Carolina 27607

Abstract

Seventeen wild-type strains of the phytopathogenic fungus Cochliobolus carbonum , tested by intraperitoneal injection into mice, were lethal within 48 hr. The lethal effect appeared to be a toxic rather than an infectious process, because death occurred within 3 hr after injection of two of the isolates and heat-killed cultures were lethal. Assays of ascospore progeny from two crosses involving three isolates indicated that the toxic metabolites were under genetic control and quantitative regulation. Studies of the toxicological, cultural, and chemical characteristics of these three strains indicated that more than one murine toxin was present.

Publisher

American Society for Microbiology

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

https://journals.asm.org/doi/pdf/10.1128/am.16.11.1719-1722.1968

Reference8 articles.

1. Fungus toxins affecting mammals;Brook P. J.;Ann. Rev. Phytopathol.,1966

2. Aflatoxin formation by Aspergillusflavus;Hesseltine C. W.;Bacteriol. Rev.,1966

3. Cochliobolus carbonum, the perfect stage of Helminthosporium carbonum;Nelson R. R.;Phytopathology,1959

4. The genetics of compatibility in Cochliobolus carbonum;Nelson R. R.;Phytopathology,1960

5. Evidence of gene pools for pathogenicity in species of Helminthosporium;Nelson R. R.;Phytopathology,1961

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Studies of the Toxicity of Helminthosporium maydis;Applied Microbiology;1972-03

2. Animal Toxicity of Phytopathogenic Fungi;Applied Microbiology;1972-01