Infant Gut Microbial Metagenome Mining of α- <scp>l</scp> -Fucosidases with Activity on Fucosylated Human Milk Oligosaccharides and Glycoconjugates-Reference-Cited by-同舟云学术

Infant Gut Microbial Metagenome Mining of α- l -Fucosidases with Activity on Fucosylated Human Milk Oligosaccharides and Glycoconjugates

Published:2022-08-31 Issue:4 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Moya-Gonzálvez Eva M.¹,Peña-Gil Nazaret²³,Rubio-del-Campo Antonio¹,Coll-Marqués José M.¹,Gozalbo-Rovira Roberto²³^ORCID,Monedero Vicente¹,Rodríguez-Díaz Jesús²³^ORCID,Yebra María J.¹^ORCID

Affiliation:

1. Laboratorio de Bacterias Lácticas y Probióticos, Departamento de Biotecnología de Alimentos, Instituto de Agroquímica y Tecnología de Alimentos (IATA-CSIC), Valencia, Spain

2. Departamento de Microbiología, Facultad de Medicina, Universidad de Valencia, Valencia, Spain

3. INCLIVA, Instituto de Investigación Sanitaría del Hospital Clínico de Valencia, Valencia, Spain

Abstract

α- l -Fucosyl residues are frequently present in many relevant glycans, such as human milk oligosaccharides (HMOs), histo-blood group antigens (HBGAs), and epitopes on cell surface glycoconjugate receptors. These fucosylated glycans are involved in a number of mammalian physiological processes, including adhesion of pathogens and immune responses.

Funder

Spanish National Plan for Scientific and Technical Research and Innovation

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.01775-22

Reference68 articles.

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3. Fucosylation in prokaryotes and eukaryotes