Role of Chromosome- and/or Plasmid-Located <i>bla</i> <sub>NDM</sub> on the Carbapenem Resistance and the Gene Stability in Escherichia coli-Reference-Cited by-同舟云学术

Role of Chromosome- and/or Plasmid-Located bla _NDM on the Carbapenem Resistance and the Gene Stability in Escherichia coli

Published:2022-08-31 Issue:4 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Sakamoto Noriko¹²,Akeda Yukihiro¹³^ORCID,Sugawara Yo¹²,Matsumoto Yuki⁴,Motooka Daisuke⁴,Iida Tetsuya¹⁴⁵^ORCID,Hamada Shigeyuki¹

Affiliation:

1. Japan-Thailand Research Collaboration Center for Infectious Diseases, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan

2. Antimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan

3. Department of Bacteriology I, National Institute of Infectious Diseases, Tokyo, Japan

4. Department of Infection Metagenomics, Genome Information Center, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan

5. Center for Infectious Disease Education and Research, Osaka University, Japan

Abstract

Carbapenem-resistant Enterobacterales (CRE) carrying bla NDM have spread worldwide since they were first reported in 2009. Many studies using whole-genome sequencing have identified the genetic structures, plasmid scaffolds of bla NDM , and mechanisms of spread via horizontal transfer.

Funder

Grants-in-Aid for Scientific Research

Japan Initiative for Global Reseach Network on Infectious Doseases

Japan Agency for Medical Research and Development

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.00587-22

Reference22 articles.

1. Characterization of a New Metallo-β-Lactamase Gene, bla NDM-1 , and a Novel Erythromycin Esterase Gene Carried on a Unique Genetic Structure in Klebsiella pneumoniae Sequence Type 14 from India