<i>Pf</i> SRPK1 Regulates Asexual Blood Stage Schizogony and Is Essential for Male Gamete Formation-Reference-Cited by-同舟云学术

Pf SRPK1 Regulates Asexual Blood Stage Schizogony and Is Essential for Male Gamete Formation

Published:2022-10-26 Issue:5 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Kumar Sudhir¹^ORCID,Baranwal Vinay K.²^ORCID,Leeb Amanda S.¹^ORCID,Haile Meseret T.¹,Oualim Kenza M. Z.¹,Hertoghs Nina¹^ORCID,Vaughan Ashley M.¹³^ORCID,Kappe Stefan H. I.¹³⁴^ORCID

Affiliation:

1. Center for Global Infectious Disease Research, Seattle Children’s Research Institute, Seattle, Washington, USA

2. Molecular Botany Lab, Swami Devanand Post Graduate College, Math-Lar, Deoria, Uttar Pradesh, India

3. Department of Global Health, University of Washington, Seattle, Washington, USA

4. Department of Pediatrics, University of Washington, Seattle, Washington, USA

Abstract

Plasmodium sexual stages represent a critical bottleneck in the parasite life cycle. Gametocytes taken up in an infectious blood meal by female anopheline mosquito get activated to form gametes and fuse to form short-lived zygotes, which transform into ookinetes to infect mosquitoes.

Funder

Seattle Children's Research Institute

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.02141-22

Reference97 articles.

1. Plasmodium asexual growth and sexual development in the haematopoietic niche of the host

2. Gametogenesis and fertilization in Plasmodium yoelii nigeriensis : a transmission electron microscope study

3. Cytology and Kinetics of microgametogenesis and fertilization inPlasmodium yoelii nigeriensis