Identification of a Linear B Cell Epitope on p54 of African Swine Fever Virus Using Nanobodies as a Novel Tool-Reference-Cited by-同舟云学术

Identification of a Linear B Cell Epitope on p54 of African Swine Fever Virus Using Nanobodies as a Novel Tool

Published:2023-06-15 Issue:3 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Zhao Huijun¹²³⁴,Wang Gaijie¹²³⁴,Dong Haoxin¹²³⁴,Wu Shuya¹²³⁴,Du Yongkun¹²³⁴,Wan Bo¹²³⁴,Ji Pengchao¹²³⁴,Wu Yanan¹²³⁴,Jiang Dawei¹²³⁴,Zhuang Guoqing¹²³⁴^ORCID,Duan Hong¹,Zhang Gaiping¹²³⁴,Zhang Angke¹²³⁴^ORCID

Affiliation:

1. College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, Henan, China

2. International Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, Henan, China

3. Henan Engineering Laboratory of Animal Biological Products, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, Henan, China

4. Longhu Modern Immunology Laboratory, Zhengzhou, Henan, China

Abstract

The ASFV p54 protein plays an important role in inducing neutralization antibodies in vivo after viral infection and is often used as a candidate protein for subunit vaccine development. The full understanding of the p54 protein epitope provides a sufficient theoretical basis for p54 as a vaccine candidate protein.

Funder

Key R&D and Promotion Project of Henan Province

河南省教育厅 | Key Scientific Research Project of Colleges and Universities in Henan Province

MOST | National Key Research and Development Program of China

MOST | National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.03362-22

Reference29 articles.