Affiliation:
1. Zhejiang Provincial Key Laboratory of Biometrology and Inspection and Quarantine, College of Life Science, China Jiliang University, Hangzhou, China
Abstract
The ppGpp-mediated stringent response is widely distributed in
Escherichia coli
,
Bacillus subtilis
,
Streptomyces
,
Staphylococcus aureus
, etc. Stringent responses give strains the ability to resist environmental stresses, and survival from nutrition starvation, virulence, long-term persistence, biofilm formation, and gut colonization. ppGpp has many targets in cells and can reprogram DNA replication, transcription, ribosome biogenesis and function, and lipid metabolism.
Funder
Zhejiang Provincial Natural Science Foundation of China
Zhejiang Provincial Program for Science and Technology Development
National Natural Science Foundation of China
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology
Cited by
3 articles.
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