Genome Mining of the Biosynthetic Gene Cluster of the Polyene Macrolide Antibiotic Tetramycin and Characterization of a P450 Monooxygenase Involved in the Hydroxylation of the Tetramycin B Polyol Segment-Reference-Cited by-同舟云学术

Genome Mining of the Biosynthetic Gene Cluster of the Polyene Macrolide Antibiotic Tetramycin and Characterization of a P450 Monooxygenase Involved in the Hydroxylation of the Tetramycin B Polyol Segment

Published:2012-09-07 Issue:15 Volume:13 Page:2234-2242
ISSN:1439-4227
Container-title:ChemBioChem
language:en
Short-container-title:ChemBioChem

Author:

Cao Bo,Yao Fen,Zheng Xiaoqing,Cui Dongbing,Shao Yucheng,Zhu Changxiong,Deng Zixin,You Delin

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cbic.201200402/fullpdf

Reference31 articles.

1. Natural Products as Sources of New Drugs over the Last 25 Years

2. Tetramycin B, a new polyene macrolide antibiotic

3. A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis

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