Hyperthermia Prevents In Vitro and In Vivo Biofilm Formation on Endotracheal Tubes

Author:

Palau Marta123ORCID,Muñoz Estela1ORCID,Larrosa Nieves234ORCID,Gomis Xavier13ORCID,Márquez Ester5ORCID,Len Oscar123ORCID,Almirante Benito123ORCID,Gavaldà Joan123ORCID

Affiliation:

1. Antibiotic Resistance Laboratory, Vall d’Hebron Research Institute, Infectious Diseases Department, Vall d’Hebron University Hospital, Barcelona, Spain

2. Spanish Network for Research in Infectious Diseases (REIPI RD19/0016), Instituto de Salud Carlos III, Madrid, Spain

3. CIBERINFEC, ISCIII-CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid, Spain

4. Microbiology Department, Vall d’Hebron University Hospital, Barcelona, Spain

5. Infectious Diseases Department, Vall d’Hebron University Hospital, Barcelona, Spain

Abstract

Biofilm-producing microorganisms are considered medically crucial since they cause 80% of the infections that occur in the human body. Medical devices such as endotracheal tubes (ETTs) can act as a reservoir for pathogens providing the surface to which microorganisms can adhere and cause biofilm-associated infections in critically ill patients.

Funder

MEC | Instituto de Salud Carlos III

Fundació la Marató de TV3

"la Caixa" Foundation

Fundación Para La Innovación Y La Prospectiva En Salud En España

Spanish Network for the Research in Infectious Diseases

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Reference42 articles.

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4. Endotracheal Tubes: Old and New

5. Biofilm formation in endotracheal tubes: association between pneumonia and the persistence of pathogens;Bauer TT;Monaldi Arch Chest Dis - Pulm Ser,2002

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