Performance and Impact on Initial Antibiotic Choice of Direct Identification of Pathogens from Pediatric Blood Culture Bottles Using an In-House MALDI-TOF MS Protocol-Reference-Cited by-同舟云学术

Performance and Impact on Initial Antibiotic Choice of Direct Identification of Pathogens from Pediatric Blood Culture Bottles Using an In-House MALDI-TOF MS Protocol

Published:2021-12-22 Issue:3 Volume:9 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Pérez-López Andrés¹²^ORCID,Elamin Nazik¹,Nabor Rhanty¹,Dumindin Sarah¹,Roscoe Diane¹,Hasan Mohammad Rubayet¹²^ORCID,Suleiman Mohammed¹^ORCID,Tang Patrick¹²

Affiliation:

1. Division of Microbiology, Department of Pathology, Sidra Medicine, Doha, Qatar

2. Weill Cornell Medical College in Qatar, Doha, Qatar

Abstract

We demonstrate the performance and early impact on the antimicrobial management of bloodstream infections of an inexpensive, in-house preparation method for direct identification of bloodstream pathogens in pediatric blood culture bottles by matrix-assisted laser desorption/ionization–time-of-flight mass spectrometry.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.01905-21

Reference22 articles.

1. Mass spectrometry-based microbiological testing for blood stream infection

2. Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry for Use with Positive Blood Cultures: Methodology, Performance, and Optimization

3. Direct identification of pathogens from positive blood cultures using matrix-assisted laser desorption-ionization time-of-flight mass spectrometry

4. Impact of Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry on the Clinical Management of Patients With Gram-negative Bacteremia: A Prospective Observational Study

5. Impact of MALDI-TOF-MS-based identification directly from positive blood cultures on patient management: a controlled clinical trial

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3. Evaluation of Immulex S. pneumoniae Omni test for the direct detection of S. pneumoniae from positive blood cultures;Heliyon;2023-11