Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry for Use with Positive Blood Cultures: Methodology, Performance, and Optimization-Reference-Cited by-同舟云学术

Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry for Use with Positive Blood Cultures: Methodology, Performance, and Optimization

Published:2017-12 Issue:12 Volume:55 Page:3328-3338
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Faron Matthew L.¹,Buchan Blake W.¹²^ORCID,Ledeboer Nathan A.¹²

Affiliation:

1. Medical College of Wisconsin, Milwaukee, Wisconsin, USA

2. Wisconsin Diagnostic Laboratories, Milwaukee, Wisconsin, USA

Abstract

ABSTRACT Early initiation of effective antibiotics for septic patients is essential for patient survival. Matrix-assisted desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) has revolutionized clinical microbiology for isolate identification and has the possibility to impact how blood culture testing is performed. This review discusses the various uses of MALDI-TOF MS for the identification and susceptibility testing of positive blood cultures, the performance of these methods, and the outcomes involved with its implementation.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00868-17

Reference56 articles.

1. Epidemiology of sepsis: An update

2. Surviving Sepsis Campaign: association between performance metrics and outcomes in a 7.5-year study

3. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock*

4. The Influence of Inadequate Antimicrobial Treatment of Bloodstream Infections on Patient Outcomes in the ICU Setting

5. Inappropriate antibiotic therapy in Gram-negative sepsis increases hospital length of stay*

Cited by 81 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Comparison of Zybio Kit and saponin in‐house method in rapid identification of bacteria from positive blood cultures by EXS2600 matrix‐assisted laser desorption ionization time‐of‐flight mass spectrometry system;Journal of Mass Spectrometry;2024-09

2. MALDI-TOF direct identification of positive blood cultures: A four-year analytical evaluation of A Triton based workflow;Diagnostic Microbiology and Infectious Disease;2024-09

3. Hospital mortality and length of stay associated with Enterobacterales positive blood cultures: a multicenter analysis;Microbiology Spectrum;2024-08-06

4. First Case of Necrotizing Fasciitis and Septicemia Caused by <i>Pigmentibacter ruber</i>;Japanese Journal of Infectious Diseases;2024-07-31

5. Comparison of the Direct Identification and Short-Term Incubation Methods for Positive Blood Cultures via MALDI-TOF Mass Spectrometry;Diagnostics;2024-07-26