SARS-CoV-2 Anti-Spike IgG Antibody and ACE2 Receptor Binding Inhibition Levels among Breakthrough Stage Veteran Patients-Reference-Cited by-同舟云学术

SARS-CoV-2 Anti-Spike IgG Antibody and ACE2 Receptor Binding Inhibition Levels among Breakthrough Stage Veteran Patients

Published:2022-12-21 Issue:6 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Chensue Stephen W.¹²^ORCID,Siler Andrew F.¹,Kim Paul S.¹³,Dimcheff Derek E.¹³,Daghfal David J.⁴,Prostko John⁴,Frias Edwin⁴,Linder Kathleen A.¹⁵,Schildhouse Richard J.¹³

Affiliation:

1. VA Ann Arbor Healthcare System, Ann Arbor, Michigan, USA

2. Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA

3. Division of Hospital Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA

4. Abbott Laboratories, CoreLab Division, Abbott Park, Illinois, USA

5. Division of Infectious Disease, University of Michigan Medical School, Ann Arbor, Michigan, USA

Abstract

Currently, clinicians have no guidance for the serologic assessment of SARS-Cov-2 postvaccination status regarding protection and risk of infection. Vaccination and boosters are administered blindly without evaluation of need or outcome at the individual level.

Funder

U.S. Department of Veterans Affairs

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.02747-22

Reference38 articles.

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3. Anti-SARS-CoV-2 antibody levels and kinetics of vaccine response: potential role for unresolved inflammation following recovery from SARS-CoV-2 infection

4. Durability of mRNA-1273 vaccine–induced antibodies against SARS-CoV-2 variants

5. Kinetics and persistence of anti‐SARS‐CoV‐2 neutralisation and antibodies after BNT162b2 vaccination in a Swiss cohort

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