Subspecies Distribution and Antimicrobial Susceptibility Testing of Mycobacterium abscessus Clinical Isolates in Madrid, Spain: a Retrospective Multicenter Study-Reference-Cited by-同舟云学术

Subspecies Distribution and Antimicrobial Susceptibility Testing of Mycobacterium abscessus Clinical Isolates in Madrid, Spain: a Retrospective Multicenter Study

Published:2023-06-15 Issue:3 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Ruedas-López Alba¹,Tato Marta²,Broncano-Lavado Antonio³,Esteban Jaime³⁴^ORCID,Ruiz-Serrano María Jesús⁵⁶⁷,Sánchez-Cueto María⁵⁶⁷,Toro Carlos⁸,Domingo Diego⁹,Cacho Juana¹⁰,Barrado Laura¹¹,López-Roa Paula¹^ORCID

Affiliation:

1. Clinical Microbiology and Parasitology Department, Instituto de Investigación, Hospital Universitario, Madrid, Spain.

2. Clinical Microbiology and Parasitology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain

3. Clinical Microbiology and Parasitology Department, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain

4. Centro de Investigación Biomédica en Red (CIBER) de Enfermedades infecciosas CIBERINFEC, Spain

5. Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

6. Clinical Microbiology and Infectious Diseases, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM) Madrid, Madrid, Spain

7. Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias- CIBERES (CB06/06/0058), Madrid, Spain

8. Clinical Microbiology and Parasitology Department, Hospital Universitario La Paz, Madrid, Spain

9. Clinical Microbiology and Parasitology Department, Hospital Universitario de La Princesa, Madrid, Spain

10. Clinical Microbiology and Parasitology Department, Hospital Universitario de Getafe, Madrid, Spain

11. Clinical Microbiology and Parasitology Department, Hospital Universitario de Móstoles, Madrid, Spain

Abstract

Infections caused by Mycobacterium abscessus (MABS) are increasingly being reported worldwide. Identifying MABS subspecies and assessing their phenotypic resistance profiles are crucial for optimal management and better patient outcomes. M. abscessus subspecies differ in erm (41) gene functionality, which is a critical determinant of macrolide resistance.

Funder

MEC | Instituto de Salud Carlos III

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.05041-22

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